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Serial Sputum Induction in Nontuberculous Mycobacterial Pulmonary Disease
PDPI Malang, 05 Jun 2020 16:55:58

Extract

The recommended procedure for diagnosis of nontuberculous mycobacterial pulmonary disease (NTM-PD) is collection of three sputum samples on separate days [1]. Sputum induction is suggested for patients unable to expectorate spontaneously. These recommendations align with evidence-based guidelines for pulmonary tuberculosis (TB) [2] but literature supporting their applicability to NTM-PD is lacking. In addition, the clinical utility of colony counts on solid media requires clarification. Early changes in semiquantitative colony counts are predictive of clinical and radiological improvement and treatment success [3] but the relationships of colony count with disease markers, such as smear status, have not been reported.

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