and Richard Costello4
1COPD Outreach, Beaumont Hospital,
Beaumont Hospital, Dublin,
of Physiotherapy, Royal College of Surgeons, Dublin, Ireland,?4Medical Directorate, Beaumont Hospital
and School of Medicine, Royal College of Surgeons, Dublin, Ireland
Chronic obstructive pulmonary
(COPD) is a complex pathological disease of the respiratory system
which is associated with a variety of comorbidities including cognitive
deficit. The purpose of this pilot study was to evaluate cognition in
COPD patients when compared to Irish norms.
Outpatients with a diagnosis
who were not in an acute exacerbation, were recruited and assess for
cognitive function using the Montreal Cognitive Assessment (MoCA)
screening tool. Demographic data including age, years of education, and
GOLD stage of disease were also collected.
The COPD Group had
MoCA scores than their Irish counterparts: COPD Group (20.77+/-4.61,
n=115) versus Irish adult norms (24.75+/-3.76, n=6113, p<0.00).
Significantly lower scores were still evident after adjusting for age
and education (mean difference 3.64, 95% CI 2.97-4.3, p<0.001).
The COPD Group was divided into two groups of disease severity (Group
1: GOLD Stages 1 and 2, Group 2: GOLD Stages 3 and 4) for further
analysis. There was no significant difference between the groups with
respect to overall MoCA score (p=0.78).
Results of this study confirm
COPD patients have significantly lower cognitive function levels
compared to Irish controls. Further analysis are currently being
conducted to see whether this impacts on hospital utilization.