Liuba
Neamtu, Svetlana Sciuca
and Rodica Selevestru
Department
of Pediatrie, State Medical and Pharmaceutical University, Chisinau, Republic
of Moldova
Aim:
of our
study was to distinguish some peculiarities of clinical manifestation
in respiratory mycoplasma infection in children.
Methods:
We
examined 330 children 7 years old and younger with community pneumonia
with wheezing. The study group110 children
(67,9%:95%CI,60,1-75) with M.pneumoniae
infection, 52(32,1%:95%CI,25-39,9) with M.hominis;
control group168 patients (50,9%:95%CI,45,4-56,4) without Mycoplasma.
In both groups males were predominate versus
females. So, in M.pneumoniae positive group males
had 54,5%:95%CI,44,8-64,1, females only 45,5%:95%CI,35,9-55,2. The same
frequency was distinguished in M.hominis-group:
55,8%:95%CI,30,5-58,7 males versus
44,2%:95%CI,30,5-58,7 females, in control group 60,1%:95%CI,52,3-67,6
males, 39,9%:95%CI,32,4-47,7 females.
Results:
Clinical manifestations in onset of pneumonia induced by M.pneumoniae
or M.hominis is characterized by dry, irritant
cough (45,2% infants, 25,0% toddlers). Fever of
37,337,6C was characteristic for M.pneumoniae
infection versus M.hominis
group with the different types of fever, such as hyperthermia,
hyperpyrexia, χ2=13,57;p<0,01.
Another peculiarity of mycoplasma infection is association with
pneumonia and wheezing (85,8%,95%CI:79,5-90,8) and it's more expressed
in infants and toddlers. In children aged 17years pneumonia
is associated with difficulties in breathing. Mycoplasma infection
represents a moderate risk of 1,76 times for pulmonary complication (RR
1,76%:95%CI,0,9-2,3;χ2=3,6;p>0,05)
versus pneumonia induced by other
microorganisms.
Conclusions:
Mycoplasma infection is characterized by
clinical polymorphism and induces longer evolution of diseases and
argues etiologic confirmation for application of macrolide treatment.
Source : http://erj.ersjournals.com/content/48/suppl_60/PA1273
Image : https://static.hospimedica.com/images/stories/articles/article_images/2016-11-30/DJB-686.jpg