Kenichiro Tanaka1, Takako Tanaka1, Yuichi Tawara1, Masaharu Asai1, Tsuyoshi
Itaki1, Ryo Kozu2 and Hideaki Senjyu1
CardioPulmonary Rehabilitation Science, Nagasaki University Graduate
School of BioMedical Sciences, Nagasaki, Japan,?2Department
of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki,
Early detection and diagnosis
obstructive pulmonary disease (COPD) is essential to maintain patients'
physical function. We have established a novel COPD screening system
for early diagnosis and treatment of 50- to 80-year-old local residents
with an FEV1% of <70%.
To verify the efficacy of
examination system according to changes in physical function during a
5-year intervention period.
All participants (21 patients
and 25 healthy subjects with an FEV1% of ≥70%) were inhabitants
of Matsuura, Nagasaki Prefecture and underwent community medical
examinations in 2006 and 2011. For 5 years, pulmonary function tests
were performed once yearly, and patient education was implemented two
to four times yearly. The evaluation items were age, body mass index,
pulmonary function test results (VC, %VC, FVC, FEV1, %FEV1, and FEV1%),
the variation of 1 year, and grip strength.
Patients with COPD were
older than healthy subjects, while all patients' pulmonary function was
significantly lower than that of healthy subjects. The %VC decreased at
a significantly lower rate in the patients. The FVC and FEV1 showed a
similar tendency; however, the rate of grip strength decline was
significantly higher in the patients.
Pulmonary function and grip
decreased with age in both the patients and healthy subjects. However,
the COPD interventions effectively suppressed the decrease in pulmonary
function in the patients to a greater degree than the normal
age-associated decline. COPD examination is now optional in Japan, but
we hope that local residents become obligated to undergo the
examination to allow for early diagnosis and treatment of potential
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