factors of postoperative pulmonary complications in bronchial asthma
and COPD patients
Takanori Numata1, Katsutoshi
Nakayama1, Nayuta Saito1, Kazuya Tsubouchi1, Nahoko Sato1, Masahiro
Yoshida1, Yusuke Kurita1, Kenji Kobayashi1, Hirofumi Utsumi1, Haruhiko
Yanagisawa1, Mitsuo Hashimoto1, Hiroshi Wakui1, Shunsuke Minagawa1, Jun
Kojima1, Hiromichi Hara1, Jun Araya1, Yumi Kaneko1 and Kazuyoshi Kuwano1
The postoperative pulmonary complication (PPC) is an important surgical
risk as common as the cardiac one, containing atelectasis, pneumonia,
and respiratory failure.
of Respiratory Diseases, The JIKEI University School of Medicine,
The purpose of this study is to evaluate the risk factors for PPC in
the patients with major respiratory underlying diseases such as
bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD)
in our university hospital.
10699 patients were surgically treated in our university hospital from
April to December in 2014. Among them, there were 68 COPD patients and
181 BA ones studied here. Eight of 68 COPD patients (11.8%) had PPC
with 6 consolidations and 2 consolidations + respiratory failures,
whereas 16 of 181 BA patients (8.8%) had PPC with 14 asthma attacks and
2 consolidations. We retrospectively evaluated physiological
background, pulmonary function, duration of surgery, and perioperative
specific treatment for pulmonary diseases to analyze the risk for PPC
in these patients.
In the BA patients, smoking index> 20 pack-year was
significantly associated with PPC [OR (95%CI) = 11.7(2.6-52.1), P=
0.0013]. In the COPD patients, induction of COPD specific treatment and
duration of surgery >300minites were significantly associated
with PPC [OR (95%CI) = 0.09(0.01-0.63), P= 0.016; OR (95%CI) =
9.5(1.4-65.3), P= 0.022, respectively]
To prevent PPC, smoking cessation in BA and induction of specific
treatment and shortening of surgery time in COPD were critically
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