Abir Hedhli1, Hajer Racil1, Sonia
Habibech1, Saoussen Bacha1, Sana Cheikhrouhou1, Naouel Chaouch1 and
Abderrahmen Mami Hospital, Ariana, Tunisia
association of pulmonary tuberculosis and diabetes presents clinical,
radiological and therapeutic particularities.
To determine the clinical and radiological characteristic and outcomes
of pulmonary tuberculosis (PT) in patients with diabetes mellitus.
Methods: we conducted a retrospective case-control study
between 2007 and 2012 on 120 patients hospitalized in a pulmonology
department for a first episode of confirmed PT. patients were divided
into two groups: group 1 (G1) represents 30 diabetics and Group 2 (G2)
included 90 non diabetic patients.
mean age was 45.5 years in G1 and was comparable to the G2. All
patients were male. Diabetes was type 2 in 76% of cases. General
symptoms were more frequent in the G2 (p=0.04). Dyspnea was more noted
in the G1 (p=0.03). The classical various types of radiological lesions
of PT were found in similar proportion in the two groups with
parenchymal shadowing the most frequent appearance in both diabetics
(86%) and control (84%). However cavitations occurred less frequently
in diabetics than controls (p=0,04). Radiological abnormalities were
bilateral and diffuse in 65% of cases of G1 against 45% in G2 (p=0.01).
There was a trend for basal lesions to occur more frequently in
diabetics than controls (p=0.005). The delay of sputum smear conversion
was longer in G1(p=0.03). An extension of the duration of treatment was
necessary in 22% of patients in the G2. Two patients died in the G1
within the first 24 hours of hospitalization.
Diabetics have severe forms of tuberculosis, atypical and often
extensive radiographic abnormalities, requiring special care to prevent
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