phenotypes of chronic obstructive pulmonary disease (COPD)
Tashkent Institute of Postgraduate Medical Education, Tashkent,
There is a big interest of
problems, related toCOPD in medicine. Selection of separate phenotypes
of COPD allows to explainclinical course at some patients and also
helps with a choice of the most adequate therapy for patients,
improving the quality of life and prognosis of disease. Potential
phenotypes of COPD are: early beginning of COPD, "young" COPD patients
(younger 50 years), COPD at women, COPD with frequent exacerbations.
Therefore, the purpose of our research was to reveal early stages of
COPD and study their phenotypes.
Materials and methods of research. 3000 persons (1600 men and 1400
women) have been investigated. By means of a special questionnaire and
peakflow meter263 persons COPD has been diagnosed. From them our
attention was attracted with "young" patients COPD - 26,6 % (70
people). 32 persons (12,2 %) from 263 were at the age from 20 till 29
years, from them 7 persons (2,6 %) - women and 25 - men (9,6 %). 38
persons (14,4 %) were at the age from 30 till 39 years (12 women (4,6
%) and 26 men (9,8 %)).
Among all patients 156 persons (59,3 %) were active smokers. 203
patients (77,2 %) had frequent exacerbations.
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risk of peripheral arterial disease in individuals with COPD
Thus, carrying out of epidemiological observations by means of special
questionnaires with peakflow meters will allow not only to reveal COPD
patients, but also to reveal "young" patients with early beginning of
COPD and to pay attention to such phenotypes COPD as ? COPD
at women?, ?COPD with frequent
Formation of phenotypes at early stages of COPD will allow to
startearly effective therapy of this disease.
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