Inhaled corticosteroid related pneumonia in real world among the patients with asthma and COPD
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Jae-Woo Kwon1, Tae Hwa Go2, Seon-Sook Han3, Seung-Hwan Lee4, Young-Ju Kim2 and Seung-Joon Lee2
Background: To investigate the occurrence of pneumonia in the real world among patients with chronic obstructive pulmonary disease (COPD), asthma, or asthma-COPD overlap syndrome (ACOS) treated with two different inhaled corticosteroids (ICS), budesonide vs fluticasone.
Methods: National registry data were collected from the Korean National Health Insurance Research Database, comprising 1,025,340 random subjects who were selected from 46,605,433 Korean residents in 2002. Patients with asthma or COPD who used budesonide or fluticasone for the first time since 2003 were enrolled. Pneumonia and ICS-related pneumonia (pneumonia with history of ICS usage within 3 months) were counted. Pneumonia was identified if ICD-10 diagnosis and antibiotics were prescribed within 2 day.
Conclusion: Pneumonia and ICS-related pneumonia were prevalent in ICS users for asthma and COPD who were older age and showed higher severity.
PDPI Sumatera Utara. 29/01/18.
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