Metabolic regulation during the co-existence of COPD and DM type2
Elene Sherozia, Liza Peirkishvili, Lali Nikoleishvili and Tamar Kakhniashvili
Background: COPD (chronic obstructive pulmonary disease) prevalence among patients with diabetes mellitus (DM)/metabolic syndrome (MetS) is high.
Aim: Definition COPD prevalence among patients with DM/MetS and evaluation of correlation between hyperglycemia and FEV1 (Forced expiratory volume in 1 sec).
Material and methods: 2800 patients were screened: smokers/ex-smokers with risk of DM, DM type2, MetS. Smokers/ex-smokers with DM/MetS-22%, smokers/ex-smokers with COPD without DM/MetS-12%, smokers/ex-smokers without COPD and DM-66%. Fasting blood glucose, Glycated hemoglobin (HbA1c), Homeostasis Model Assessment (HOMA), spirometry was done.
Conclusion: COPD spreading is high in patients with glucose metabolism disturbance. It negatively affects FEV1. Complications frequency (25% vs 11%) is significantly higher (P<0.005) in COPD and DM/MetS coexistence, rather than only in COPD. Spirometry screening is necessary in patients with glucose metabolism disturbance for early detection of COPD.
PDPI Malang. 02/02/18.
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