Assessment of lung volumes and capacities in bronchodilator reversibility changes of hyperinflation of COPD
Images : https://images.onhealth.com/images/slideshow/chronic-obstructive-pulmonary-disorder-copd-s9-photo-of-bronchodilator.jpg
Wafaa Gadallah1, Atef Farouk1, Abd Elazeem Aboelfadl1 and Manal Alkhawaga1
Background: Bronchodilator reversibility in COPD patients traditionally used FEV1 as the marker of reversibility but FEV1 has been demonstrated to lack sensitivity in some cases and is generally a poor predictor of improvement in patients with advanced COPD.
Objective: Validate the use of lung volumes and capacities as a noninvasive technique capable of assessment of bronchodilator reversibility changes in hyperinflated patients with COPD. Study design and intervention: Randomized controlled study included 110 hyperinflated stable COPD patients (TLC >120% predicted) They were classified into mild (n= 46) moderate (n= 32) and severe hyperinflation (n= 32).Main outcome measures: Measurement of IC, RV, FRC or TLC before and after bronchodilator administration together with standard FEV1 and FVC.
Conclusion: lung volumes and capacities along with the standard spirometric indexes be measured when determining bronchodilator responsiveness in patients with baseline hyperinflation should have closer attention.
PDPI Surakarta. 06/03/18.
Halaman Siap Cetak
Kirimkan Pada Rekan