Perhimpunan Dokter Paru Indonesia - Asthma phenotypes in children: Allergic versus non allergic
Asthma phenotypes in children: Allergic versus non allergic
Tanggal: 18/04/17
Topik: Medis


To describe the clinical similarities and differences between atopic and non-atopic asthmatics in children.

Asthma phenotypes in children: Allergic versus non allergic




Seyed Alireza Mahdaviani1,Seyed Amir Mohajerani1,Mohammad Fakhri1,Mazaher Ebrahimi Ebrahimi1 andAli Akbar Velayati1
1Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), ShahidBeheshti University of Medical Sciences, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), ShahidBeheshti University of Medical Sciences, Tehran, Islamic Republic of Iran


Background: The aim of this study is to describe the clinical similarities and differences between atopic and non-atopic asthmatics in children.

Methods: In this cross-sectional study, 95 asthmatics (75 allergics and 20 nonallergics) children were included and the demographic, clinical, and familial characteristics were compared across the groups.

Results: There was no significant difference between important factors like sex (p=1.00), age of onset (0.75) and severity (0.70), and family history among two groups (P > 0.05). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28 3.19 and 9.75 2.35 years respectively, p <0.05).

Conclusion: The controversy over the presence of non-atopic asthma as a completely distinct clinical entity in children lingers. Our study suggests that phenotypes of allergic and non-allergic asthma in children are not highly distinct, along with the immunological similarities recently published.

http://erj.ersjournals.com/content/48/suppl_60/PA4394







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