BV Muralimohan1, Gayatri Ekbote1, Syed Zulkharnain Tousheed1 and
Narayana Health, Bangalore, Karnataka India
Cardiovascular disease (CVD) [comprising coronary artery disease (CAD),
cerebro-vascular disease (CeVD), peripheral vascular disease (PVD)] and
chronic obstructive pulmonary disease (COPD) are major health problems.
COPD may contribute to the disease severity in patients with CVD.
The COPD-CVD association occurs not by chance, but due to shared risk
factors and a common pro-inflammatory predisposition. Most studies
describe the prevalence of CVD in COPD; this study looked for COPD in
patients with CVD.
To study the occurrence of COPD among patients with proven CVD
To study the association of COPD severity and co-morbid CVD.
Study design: This
study was conducted at Narayana Health City, among 501 consecutive
subjects with proven CVD. COPD was diagnosed by a screening
questionnaire and confirmed by spirometry.
There were 501 cases of CVD, 419 [82%] males, 82 [16.4%] females (mean
age 66.74 years). COPD was diagnosed in 113 [23%], higher than expected
for the general population.There were equal numbers in the GOLD low
(Group A +B) and high risk (Groups C+D) groups. Smoking was the
commonest risk factor.Of 99 patients had >1 vascular disease,
48.48% had COPD.
COPD did not occur more frequently in those with CAD alone (p= 0.782),
but was significantly associated with CeVD [n=8 (12.3%, p = 0.034)],
and with PVD [n=17 26.2%, p = 0.047)].
COPD contributes to morbidity, and perhaps mortality in CVD patients.
Co-existing COPD is commoner in those with >1 vasculopathy.
Patients with vascular diseases should be screened for COPD.